hydrochlorothiazide

Ligand Id: 4836
Ligand name hydrochlorothiazide

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 1
Topological polar surface area 135.12
Molecular weight 296.96
XLogP -1.26
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1959))
IUPAC Name
6-chloro-1,1-dioxo-3,4-dihydro-2H-1$l^{6},2,4-benzothiadiazine-7-sulfonamide
International Nonproprietary Names
INN number INN
841 hydrochlorothiazide
Synonyms
Apo-hydro®
Database Links
CAS Registry No. 58-93-5 (source: Scifinder)
ChEMBL Ligand CHEMBL435
DrugBank Ligand DB00999
PubChem CID 3639
Search Google for chemical match using the InChIKey JZUFKLXOESDKRF-UHFFFAOYSA-N
Search Google for chemicals with the same backbone JZUFKLXOESDKRF
Search PubMed clinical trials hydrochlorothiazide
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Wikipedia Hydrochlorothiazide
Comments
Hydrochlorothiazide is the prototypical thiazide diuretic drug.