metolazone

Ligand Id: 4838
Ligand name metolazone

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 100.88
Molecular weight 365.06
XLogP 2.55
No. Lipinski's rules broken 0

Molecular properties generated using the CDK


Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1973))
DrugBank groups Approved
IUPAC Name
7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
International Nonproprietary Names
INN number INN
2627 metolazone
Database Links
CAS Registry No. 17560-51-9 (source: Scifinder)
ChEMBL Ligand CHEMBL878
DrugBank Ligand DB00524
PubChem CID 4170
Search Google for chemical match using the InChIKey AQCHWTWZEMGIFD-UHFFFAOYSA-N
Search Google for chemicals with the same backbone AQCHWTWZEMGIFD
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Wikipedia Metolazone
ZINC ZINC00601254