tumour necrosis factor membrane form

Ligand id: 5073

Name: tumour necrosis factor membrane form

Abbreviated name: TNF membrane form

Species: Human

This ligand is also described as a target entry: tumor necrosis factor

Classification
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
TNF tumor necrosis factor Human prepro-tumor necrosis factor DIF, TNFA, TNF-alpha, TNFSF2, TNF superfamily, member 2, tumor necrosis factor (TNF superfamily, member 2)
Synonyms
cachectin
necrosin
TNFα
Database Links
DrugBank Target P01375 (Hs)
Ensembl Gene ENSG00000204490 (Hs)
UniProtKB P01375 (Hs)
Wikipedia Tumor_necrosis_factor-alpha
Comments
The TNFSF2 precursor is also cleaved into a secreted (shed) form of the ligand