Classification
Compound class	Endogenous peptide in human, mouse or rat

Gene/Precursor

Gene symbol Gene name Species Precursor protein name Synonyms TNF tumor necrosis factor Human prepro-tumor necrosis factor DIF, TNFA, TNF-alpha, TNFSF2, TNF superfamily, member 2, tumor necrosis factor (TNF superfamily, member 2)

Synonyms

cachectin

necrosin

TNFα

Database Links
DrugBank Target	P01375 (Hs)
Ensembl Gene	ENSG00000204490 (Hs)
UniProtKB	P01375 (Hs)
Wikipedia	Tumor_necrosis_factor-alpha

Comments

TNFα is a pro-inflammatory, acute phase cytokine involved in systemic inflammation. The TNFSF2 precursor is also cleaved into a membrane-bound form of the ligand.