tumour necrosis factor membrane form

Ligand Id: 5073
Ligand name tumour necrosis factor membrane form
Abbreviated name TNF membrane form
Species Human
This ligand is also described as a target entry: tumor necrosis factor


Classification
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor
Gene symbol Gene name Species Protein name Synonyms
TNF tumor necrosis factor Human prepro-tumor necrosis factor DIF, TNFA, TNF-alpha, TNFSF2, TNF superfamily, member 2, tumor necrosis factor (TNF superfamily, member 2)
Synonyms
cachectin
cytotoxin
DIF
necrosin
TNF
TNFα
TNFSF2
tumour necrosis factor
Database Links
Ensembl Gene ENSG00000204490 (Hs)
UniProtKB P01375 (Hs)
Wikipedia Tumor_necrosis_factor-alpha
Comments
The TNFSF2 precursor is also cleaved into a secreted (shed) form of the ligand