dexlansoprazole

Ligand id: 5487

Name: dexlansoprazole

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 87.08
Molecular weight 369.08
XLogP 2.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2009); (1995 as lansoprazole))
IUPAC Name
2-[(R)-{[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methane}sulfinyl]-1H-1,3-benzodiazole
International Nonproprietary Names
INN number INN
8524 dexlansoprazole
6397 lansoprazole
Synonyms
(+)-lansoprazol | (R)-lansoprazole | Dexilant SoluTab® | Dexilant® | Kapidex® | T 168390 | TAK 390
Database Links
CAS Registry No. 138530-94-6
ChEBI CHEBI:6375
ChEMBL Ligand CHEMBL1201863
DrugBank Ligand DB00448
PubChem CID 9578005
Search Google for chemical match using the InChIKey MJIHNNLFOKEZEW-RUZDIDTESA-N
Search Google for chemicals with the same backbone MJIHNNLFOKEZEW
Search PubMed clinical trials lansoprazole
Search PubMed titles lansoprazole
Search PubMed titles/abstracts lansoprazole
Search UniChem for chemical match using the InChIKey MJIHNNLFOKEZEW-RUZDIDTESA-N
Search UniChem for chemicals with the same backbone MJIHNNLFOKEZEW
Wikipedia Lansoprazole, Dexlansoprazole
Comments
In addition to being an approved drug with INN dexlansoprazole, (R)-lansoprazole is also a component of the approved drug lansoprazole, a racemic mixture of (R)- and (S)- stereoisomers. Use this PubChem link to view all 3 isomers.