Ligand id: 5487

Name: dexlansoprazole

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 87.08
Molecular weight 369.08
XLogP 2.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of erosive oesophagitis and non-erosive gastro-oesophageal reflux disease.
Mechanism Of Action and Pharmacodynamic Effects
Proton pump inhibitor that inhibits the (H+,K+)-ATPase enzyme system in gastric parietal cells, thereby blocking the final step of acid production.