L-659,699

Ligand id: 5886

Name: L-659,699

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 83.83
Molecular weight 324.19
XLogP 3.92
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2E,4E,7R)-11-[(2R,3R)-3-(hydroxymethyl)-4-oxooxetan-2-yl]-3,5,7-trimethylundeca-2,4-dienoic acid
Synonyms
antibiotic 1233A | hymeglusin | L 659699
Database Links
CAS Registry No. 29066-42-0 (source: Scifinder)
ChEMBL Ligand CHEMBL470269
PubChem CID 6440895
Search Google for chemical match using the InChIKey ODCZJZWSXPVLAW-KXCGKLMDSA-N
Search Google for chemicals with the same backbone ODCZJZWSXPVLAW
Search UniChem for chemical match using the InChIKey ODCZJZWSXPVLAW-KXCGKLMDSA-N
Search UniChem for chemicals with the same backbone ODCZJZWSXPVLAW
Comments
Hymeglusin is a fungal beta-lactone. It irreversibly inhibits cytosolic 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase activity