enalapril

Ligand id: 6322

Name: enalapril

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 95.94
Molecular weight 376.2
XLogP 4.14
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1985))
Is prodrug? Yes
Active form enalaprilat
IUPAC Name
(2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid
International Nonproprietary Names
INN number INN
5117 enalapril
Synonyms
Enaladex® | Vasotec®
Database Links
CAS Registry No. 75847-73-3 (source: PubChem)
ChEBI CHEBI:4784
ChEMBL Ligand CHEMBL578
DrugBank Ligand DB00584
GtoPdb PubChem SID 178102940
PubChem CID 5388962
Search Google for chemical match using the InChIKey GBXSMTUPTTWBMN-XIRDDKMYSA-N
Search Google for chemicals with the same backbone GBXSMTUPTTWBMN
Search PubMed clinical trials enalapril
Search PubMed titles enalapril
Search PubMed titles/abstracts enalapril
Search UniChem for chemical match using the InChIKey GBXSMTUPTTWBMN-XIRDDKMYSA-N
Search UniChem for chemicals with the same backbone GBXSMTUPTTWBMN
Wikipedia Enalapril
Comments
Pro-drug for elanoprilat