Classification ![]() |
|
| Compound class | Antibody |
| Approved drug? | Yes (source: FDA (2011), EMA (2012)) |
International Nonproprietary Names ![]() |
|
| INN number | INN |
| 8739 | aflibercept |
Synonyms ![]() |
| AVE0005 |
| Eylea® |
| VEGF Trap |
| Zaltrap® |
| ziv-aflibercept |
Database Links ![]() |
|
| Specialist databases | |
| IMGT/mAb-DB | 214 |
| Other databases | |
| CAS Registry No. | 862111-32-8 |
| ChEMBL Ligand | CHEMBL1742982 |
| DrugBank Ligand | DB08885 |
| PubChem SID | 135347926 |
| Search PubMed clinical trials | aflibercept |
| Search PubMed titles | aflibercept |
| Search PubMed titles/abstracts | aflibercept |
| Wikipedia | Aflibercept |
| Comments |
| Alfibercept is a fusion protein combining the Fc portion of human IgG with the ligand binding domains of the VEGRF1 and VEGRF2 receptors. |