glipizide

Ligand id: 6821

Name: glipizide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 138.53
Molecular weight 445.18
XLogP 3.24
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1984))
IUPAC Name
N-[2-(4-{[(cyclohexylcarbamoyl)amino]sulfonyl}phenyl)ethyl]-5-methylpyrazine-2-carboxamide
International Nonproprietary Names
INN number INN
3090 glipizide
Synonyms
CP-28720 | Glucotrol® | K-4024
Database Links
CAS Registry No. 29094-61-9
ChEMBL Ligand CHEMBL1073
DrugBank Ligand DB01067
GtoPdb PubChem SID 178103427
PubChem CID 3478
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Wikipedia Glipizide
Comments
A sulfonylurea family drug inhibiting sulfonylurea receptor 1 (ABCC8)/Kir6.2 (KCNJ11).