Ligand id: 6969

Name: pegfilgrastim

Compound class Peptide or derivative
Approved drug? Yes (FDA and EMA (2002))
International Nonproprietary Names
INN number INN
8114 pegfilgrastim
Database Links
Specialist databases
IMGT/mAb-DB 616
Other databases
CAS Registry No. 208265-92-3 (source: Scifinder)
ChEMBL Ligand CHEMBL1201568
DrugBank Ligand DB00019
GtoPdb PubChem SID 178103549
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Wikipedia Pegfilgrastim
This is a PEGylated version of recombinant human G-CSF. Pegylation increases circulating half-life.

A biosimilar agent called MYL-1401H (Mylan) is being evaluated in Phase 3 breast cancer trial NCT02467868 in direct comparison to the originator product Neulasta®.