busulfan

Ligand id: 7136

Name: busulfan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Topological polar surface area 103.5
Molecular weight 246.02
XLogP -1.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1954), EMA (2003))
IUPAC Name
4-(methanesulfonyloxy)butyl methanesulfonate
International Nonproprietary Names
INN number INN
564 busulfan
Synonyms
Busulfex IV®
Myleran®
Database Links
CAS Registry No. 55-98-1
ChEMBL Ligand CHEMBL820
DrugBank Ligand DB01008
PubChem CID 2478
Search Google for chemical match using the InChIKey COVZYZSDYWQREU-UHFFFAOYSA-N
Search Google for chemicals with the same backbone COVZYZSDYWQREU
Search PubMed clinical trials busulfan
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Wikipedia Busulfan
Comments
Busulfan is a DNA alkylating agent. It has an immunosuppressive effect on bone marrow, especially inhibiting growth of granulocytes.