ethosuximide

Ligand id: 7182

Name: ethosuximide

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 49.66
Molecular weight 141.08
XLogP 0.75
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1960))
IUPAC Name
3-ethyl-5-hydroxy-3-methyl-3,4-dihydro-2H-pyrrol-2-one
International Nonproprietary Names
INN number INN
1077 ethosuximide
Synonyms
CI-366 | CN-10395 | PM-671 | Zarontin®
Database Links
CAS Registry No. 77-67-8
ChEMBL Ligand CHEMBL696
DrugBank Ligand DB00593
GtoPdb PubChem SID 178103757
PubChem CID 3291
Search Google for chemical match using the InChIKey HAPOVYFOVVWLRS-UHFFFAOYSA-N
Search Google for chemicals with the same backbone HAPOVYFOVVWLRS
Search PubMed clinical trials ethosuximide
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Search UniChem for chemical match using the InChIKey HAPOVYFOVVWLRS-UHFFFAOYSA-N
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Wikipedia Ethosuximide
Comments
Ethosuximide is a succinimide anticonvulsant. It is often preferred over valproic acid as it does not produce the same hepatotoxicity.