ethosuximide

Ligand id: 7182

Name: ethosuximide

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 49.66
Molecular weight 141.08
XLogP 0.75
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Ethosuximide is used to treat absence type epileptic and myoclonic seizures.
Mechanism Of Action and Pharmacodynamic Effects
Ethosuximide blocks activity of transient (T-type) voltage gated calcium channels. CACNA1E, CACNA1H and CACNA1I alpha subunits are detailed in this database, in the Voltage-gated calcium channels section. See the DrugBank link for further details explaining the predicted molecular mechanism of action of this drug.
External links