lisdexamfetamine

Ligand id: 7213

Name: lisdexamfetamine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 84.63
Molecular weight 263.2
XLogP 3.64
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2007))
Is prodrug? Yes
Active form dexamfetamine
IUPAC Name
(2S)-2,6-diamino-N-[(2S)-1-phenylpropan-2-yl]hexanimidic acid
International Nonproprietary Names
INN number INN
8690 lisdexamfetamine
Synonyms
NRP104 | Vyvanse®
Database Links
CAS Registry No. 608137-32-2
ChEMBL Ligand CHEMBL1201222
DrugBank Ligand DB01255
GtoPdb PubChem SID 178103788
PubChem CID 11597698
Search Google for chemical match using the InChIKey VOBHXZCDAVEXEY-JSGCOSHPSA-N
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Search UniChem for chemical match using the InChIKey VOBHXZCDAVEXEY-JSGCOSHPSA-N
Search UniChem for chemicals with the same backbone VOBHXZCDAVEXEY
Wikipedia Lisdexamfetamine
Comments
This drug is a prodrug of dexamphetamine. The amphetamine is released more slowly from this prodrug than by administering active amphetamine directly.