fospropofol

Ligand id: 7475

Name: fospropofol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 85.8
Molecular weight 288.11
XLogP 3.14
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2008))
Is prodrug? Yes
Active form propofol
IUPAC Name
[2,6-di(propan-2-yl)phenoxy]methyl dihydrogen phosphate
International Nonproprietary Names
INN number INN
8696 fospropofol
Synonyms
Lusedra®
Database Links
CAS Registry No. 258516-89-1 (source: Scifinder)
ChEMBL Ligand CHEMBL1201766
GtoPdb PubChem SID 187051778
PubChem CID 3038498
Search Google for chemical match using the InChIKey QVNNONOFASOXQV-UHFFFAOYSA-N
Search Google for chemicals with the same backbone QVNNONOFASOXQV
Search PubMed clinical trials fospropofol
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Search UniChem for chemical match using the InChIKey QVNNONOFASOXQV-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone QVNNONOFASOXQV
Wikipedia Fospropofol
Comments
Fospropofol is a prodrug which undergoes hepatic conversion to the active moeity, propofol.