propofol

Ligand id: 5464

Name: propofol

View more information in the IUPHAR Pharmacology Education Project: propofol

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	0
Hydrogen bond donors	1
Rotatable bonds	2
Topological polar surface area	20.23
Molecular weight	178.14
XLogP	4.42
No. Lipinski's rules broken	0

Molecular properties generated using the CDK

IUPAC Name
2,6-bis(propan-2-yl)phenol

IUPAC Name

2,6-bis(propan-2-yl)phenol

International Nonproprietary Names
INN number	INN
5073	propofol

Synonyms
2,6-diisopropylphenol \| Diprivan® \| ICI 35868

Synonyms

2,6-diisopropylphenol | Diprivan® | ICI 35868

Comments
Propofol is a short-acting (lasting 5-10 minutes) sedative. It is on the World Health Organization's List of Essential Medicines (link to 2015 list).

Comments

Propofol is a short-acting (lasting 5-10 minutes) sedative. It is on the World Health Organization's List of Essential Medicines (link to 2015 list).

Database Links
CAS Registry No.	2078-54-8
ChEBI	CHEBI:44915
ChEMBL Ligand	CHEMBL526
DrugBank Ligand	DB00818
GtoPdb PubChem SID	178102114
PubChem CID	4943
RCSB PDB Ligand	PFL
Search Google for chemical match using the InChIKey	OLBCVFGFOZPWHH-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	OLBCVFGFOZPWHH
Search PubMed clinical trials	propofol
Search PubMed titles	propofol
Search PubMed titles/abstracts	propofol
Search UniChem for chemical match using the InChIKey	OLBCVFGFOZPWHH-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	OLBCVFGFOZPWHH
Wikipedia	Propofol