propofol

Ligand id: 5464

Name: propofol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 0
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 20.23
Molecular weight 178.14
XLogP 4.42
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1989))
Prodrug fospropofol
IUPAC Name
2,6-bis(propan-2-yl)phenol
International Nonproprietary Names
INN number INN
5073 propofol
Synonyms
2,6-diisopropylphenol | Diprivan® | ICI 35868
Database Links
CAS Registry No. 2078-54-8
ChEBI CHEBI:44915
ChEMBL Ligand CHEMBL526
DrugBank Ligand DB00818
PubChem CID 4943
RCSB PDB Ligand PFL
Search Google for chemical match using the InChIKey OLBCVFGFOZPWHH-UHFFFAOYSA-N
Search Google for chemicals with the same backbone OLBCVFGFOZPWHH
Search PubMed clinical trials propofol
Search PubMed titles propofol
Search PubMed titles/abstracts propofol
Search UniChem for chemical match using the InChIKey OLBCVFGFOZPWHH-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone OLBCVFGFOZPWHH
Wikipedia Propofol
Comments
Propofol is a short-acting (lasting 5-10 minutes) sedative. It is on the World Health Organization's List of Essential Medicines (link to 2015 list).