edoxaban

Ligand id: 7575

Name: edoxaban

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 164.87
Molecular weight 547.18
XLogP 0.4
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2015))
IUPAC Name
N'-(5-chloropyridin-2-yl)-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-[(5-methyl6,7-dihydro-4H-[1,3]thiazolo[5,4-c]pyridine-2-carbonyl)amino]cyclohexyl]oxamide
International Nonproprietary Names
INN number INN
8982 edoxaban
Synonyms
DU-176 | DU-176b | edoxaban tosylate | Lixiana® | Savaysa®
Database Links
CAS Registry No. 480449-70-5
ChEMBL Ligand CHEMBL1269025
PubChem CID 10280735
Search Google for chemical match using the InChIKey HGVDHZBSSITLCT-JLJPHGGASA-N
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Search PubMed clinical trials edoxaban
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Search UniChem for chemical match using the InChIKey HGVDHZBSSITLCT-JLJPHGGASA-N
Search UniChem for chemicals with the same backbone HGVDHZBSSITLCT
Wikipedia Edoxaban
Comments
Edoxaban is an oral, once-daily factor Xa inhibitor anticoagulant.
Marketed formulations contain edoxaban tosylate (PubChem CID 44610678).