edoxaban

Ligand id: 7575

Name: edoxaban

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 164.87
Molecular weight 547.18
XLogP 0.4
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

References
1. Pinto DJ, Smallheer JM, Cheney DL, Knabb RM, Wexler RR. (2010)
Factor Xa inhibitors: next-generation antithrombotic agents.
J. Med. Chem.53 (17): 6243-74. [PMID:20503967]