andexanet alfa

Ligand id: 7576

Name: andexanet alfa

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Classification
Compound class Peptide or derivative
Approved drug? Yes (FDA (2018))
International Nonproprietary Names
INN number INN
9883 andexanet alfa
Synonyms
Andexxa® | coagulation factor Xa (recombinant), inactivated-zhzo | PRT064445 | PRT4445 | r-antidote
Comments
Andexanet alfa is a recombinant modified human Factor Xa (FXa) protein that acts as a mimetic of endogenous human factor Xa, and which was developed as a universal antidote to reverse thhe anticoagulant effects of direct or indirect FXa inhibitors. Information regarding the invention of andexanet alfa is available in patent WO2009042962 [2].
Database Links
GtoPdb PubChem SID 223365912
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UniParc UPI0001AD5DCA
Wikipedia Andexanet_alfa