icotinib

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Ligands
icotinib

Ligand id: 7641

Name: icotinib

Structure and Physico-chemical Properties

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	5
Hydrogen bond donors	1
Rotatable bonds	2
Topological polar surface area	74.73
Molecular weight	391.15
XLogP	2.93
No. Lipinski's rules broken	0

Molecular properties generated using the CDK

Summary
Biological activity
Clinical data
References
Structure
Similar ligands

Classification
Compound class	Synthetic organic
Approved drug?	Yes

IUPAC Name
N-(3-ethynylphenyl)-7H,8H,10H,11H,13H,14H-1,4,7,10-tetraoxacyclododeca[2,3-g]quinazolin-4-amine

IUPAC Name

N-(3-ethynylphenyl)-7H,8H,10H,11H,13H,14H-1,4,7,10-tetraoxacyclododeca[2,3-g]quinazolin-4-amine

Synonyms
BPI-2009H
Conmana®

Synonyms

BPI-2009H

Conmana®

Database Links
CAS Registry No.	610798-31-7 (source: SciFinder)
ChEMBL Ligand	CHEMBL2087361
PubChem CID	22024915
Search Google for chemical match using the InChIKey	QQLKULDARVNMAL-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	QQLKULDARVNMAL
Wikipedia	Icotinib

Comments
Icotinib is a selective, orally available epidermal growth factor receptor tyrosine kinase inhibitor [1-3]. Click here to view icotinib trials registered with ClinicalTrials.gov.

Comments

Icotinib is a selective, orally available epidermal growth factor receptor tyrosine kinase inhibitor [1-3]. Click here to view icotinib trials registered with ClinicalTrials.gov.