Classification
Compound class	Synthetic organic

IUPAC Name

3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-[6-[4-(4-ethylpiperazin-1-yl)anilino]pyrimidin-4-yl]-1-methylurea

International Nonproprietary Names
INN number	INN
10032	infigratinib

Synonyms

BGJ 398 | BGJ-398 | BGJ398 | NVP-BGJ398

Comments

The discovery and synthesis of infigratinib (BGJ-398) is described in [1], where it is compound 1h. It is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs) with potential antiangiogenic and antineoplastic activities [1].

Database Links
CAS Registry No.	872511-34-7
ChEMBL Ligand	CHEMBL1852688
GtoPdb PubChem SID	223366206
PubChem CID	53235510
RCSB PDB Ligand	07J
Search Google for chemical match using the InChIKey	QADPYRIHXKWUSV-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	QADPYRIHXKWUSV
Search PubMed clinical trials	infigratinib
Search PubMed titles	infigratinib
Search PubMed titles/abstracts	infigratinib
Search UniChem for chemical match using the InChIKey	QADPYRIHXKWUSV-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	QADPYRIHXKWUSV
SynPHARM	80719 (in complex with fibroblast growth factor receptor 1)