voxtalisib

Ligand id: 7964

Name: voxtalisib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 3
Rotatable bonds 11
Topological polar surface area 149.15
Molecular weight 599.18
XLogP 5.44
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-[4-[[3-(3,5-dimethoxyanilino)quinoxalin-2-yl]sulfamoyl]phenyl]-3-methoxy-4-methylbenzamide
International Nonproprietary Names
INN number INN
9709 voxtalisib
Synonyms
SAR-245409 | SAR245409 | XL765
Database Links
CAS Registry No. 934493-76-2
PubChem CID 49867926
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Comments
Voxtalisib is an orally bioavailable small molecule inhibitor of phosphatidylinositol 3 kinase (PI3K) and mammalian target of rapamycin (mTOR) kinases in the PI3K/mTOR signaling pathway, with potential antineoplastic activity [1].