IFN-β1a (recombinant human)

Ligand id: 8339

Name: IFN-β1a (recombinant human)

Classification
Compound class Peptide or derivative
Approved drug? Yes (FDA (1996))
International Nonproprietary Names
INN number INN
5380 interferon beta
Synonyms
Avonex® | Rebif®
Database Links
DrugBank Ligand DB00060
Search PubMed clinical trials interferon beta
Search PubMed titles interferon beta
Search PubMed titles/abstracts interferon beta
Wikipedia Interferon_beta_1a
Comments
Compared to the sequence of the endogenous peptide, IFN-β1a has a Gln to Cys substitution at position 17 and retains the Asn glycosylation site at position 80. Whilst the regular form of this peptide has to be injected 1-3 times/week, a PEGylated form (peginterferon beta-1a) is now available that requires less frequent administration (on a fortnightly basis).