esketamine

Ligand id: 9152

Name: esketamine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 29.1
Molecular weight 237.09
XLogP 2.97
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(2S)-2-(2-chlorophenyl)-2-methylaminocyclohexan-1-one
International Nonproprietary Names
INN number INN
7884 esketamine
Synonyms
(S)-Ketamine
Comments
As the ketamine S enatiomer esketamine is twice as potent and has a more medically useful pharmacological action than the racemate ketamine racemate. Part of this advantage arises from inhibition of dopamine transporters.
Database Links
ChEMBL Ligand CHEMBL395091
GtoPdb PubChem SID 315661237
PubChem CID 182137
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Wikipedia Esketamine