phenylarsine oxide

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Ligands
phenylarsine oxide

Ligand id: 9201

Name: phenylarsine oxide

Abbreviated name: PAO

Structure and Physico-chemical Properties

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	1
Hydrogen bond donors	0
Rotatable bonds	1
Topological polar surface area	17.07
Molecular weight	167.96
XLogP	2.19
No. Lipinski's rules broken	0

Molecular properties generated using the CDK

Classification
Compound class	Synthetic organic

IUPAC Name
arsorosobenzene

IUPAC Name

arsorosobenzene

Synonyms
arzene \| oxophenylarsine \| PAO \| phenylarsenoxide

Synonyms

arzene | oxophenylarsine | PAO | phenylarsenoxide

Database Links
ChEMBL Ligand	CHEMBL477683
GtoPdb PubChem SID	315661277
PubChem CID	4778
RCSB PDB Ligand	PA0
Search Google for chemical match using the InChIKey	BQVCCPGCDUSGOE-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	BQVCCPGCDUSGOE
Search UniChem for chemical match using the InChIKey	BQVCCPGCDUSGOE-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone	BQVCCPGCDUSGOE

Comments
PAO inhibits type III PI 4-kinases, whereas it is relatively ineffective against the type II in in vitro kinase assays. Among the type III enzymes, PI4KIIIα is significantly more sensitive to PAO than the type IIIβ form [1].

Comments

PAO inhibits type III PI 4-kinases, whereas it is relatively ineffective against the type II in in vitro kinase assays. Among the type III enzymes, PI4KIIIα is significantly more sensitive to PAO than the type IIIβ form [1].