U-47700

Ligand id: 9282

Name: U-47700

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 23.55
Molecular weight 328.11
XLogP 3.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3,4-dichloro-N-[(1R,2R)-2-(dimethylamino)cyclohexyl]-N-methylbenzamide
Synonyms
compound 1 [PMID: 2999404]
Database Links
CAS Registry No. 82657-23-6 (source: PubChem)
ChEMBL Ligand CHEMBL277572
PubChem CID 13544016
Search Google for chemical match using the InChIKey JGPNMZWFVRQNGU-HUUCEWRRSA-N
Search Google for chemicals with the same backbone JGPNMZWFVRQNGU
Search UniChem for chemical match using the InChIKey JGPNMZWFVRQNGU-HUUCEWRRSA-N
Search UniChem for chemicals with the same backbone JGPNMZWFVRQNGU
Comments
U-47700 is a selective μ-opioid receptor agonist [2], with in vivo effects similar to other potent opioid agonists (analgesia, sedation, euphoria, constipation and respiratory depression). Illicit use and fatalities caused by U-47700 [1,3-4] has prompted action to schedule the compound or make it illegal in some jurisdictions.