fenoldopam

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Ligands
fenoldopam

Ligand id: 939

Name: fenoldopam

Structure and Physico-chemical Properties

2D Structure

Calculated Physico-chemical Properties
Hydrogen bond acceptors	1
Hydrogen bond donors	4
Rotatable bonds	1
Topological polar surface area	72.72
Molecular weight	305.08
XLogP	2.08
No. Lipinski's rules broken	0

Molecular properties generated using the CDK

Classification
Compound class	Synthetic organic
Approved drug?	Yes (source: FDA (1997))

IUPAC Name
6-chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol

IUPAC Name

6-chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol

International Nonproprietary Names
INN number	INN
4673	fenoldopam

Synonyms
Corlopam®
SK&F-82526J
SK-82526-J

Synonyms

Corlopam®

SK&F-82526J

SK-82526-J

Database Links
BindingDB Ligand	50020681
CAS Registry No.	67227-56-9
ChEBI	CHEBI:5002
ChEMBL Ligand	CHEMBL588
DrugBank Ligand	DB00800
PharmGKB Drug	PA164784034
PubChem CID	3341
Search Google for chemical match using the InChIKey	TVURRHSHRRELCG-UHFFFAOYSA-N
Search Google for chemicals with the same backbone	TVURRHSHRRELCG
Search PubMed clinical trials	fenoldopam
Search PubMed titles	fenoldopam
Search PubMed titles/abstracts	fenoldopam
Wikipedia	Fenoldopam

Comments
The approved drug fenoldopam is a racemic mixture of (+)-SKF-82526 and (-)-SKF-82526 stereoisomers. We show the non-isomeric structure to represent this mixture. Marketed formulations may contain fenoldopam mesylate (PubChem CID 49659).

Comments

The approved drug fenoldopam is a racemic mixture of (+)-SKF-82526 and (-)-SKF-82526 stereoisomers. We show the non-isomeric structure to represent this mixture. Marketed formulations may contain fenoldopam mesylate (PubChem CID 49659).