(-)-SKF-82526

Ligand id: 985

Name: (-)-SKF-82526

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 4
Rotatable bonds 1
Topological polar surface area 72.72
Molecular weight 305.08
XLogP 2.08
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
(1R)-6-chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
International Nonproprietary Names
INN number INN
4673 fenoldopam
Database Links
DrugBank Ligand DB00800
PubChem CID 12668023
Search Google for chemical match using the InChIKey TVURRHSHRRELCG-CYBMUJFWSA-N
Search Google for chemicals with the same backbone TVURRHSHRRELCG
Search PubMed clinical trials fenoldopam
Search PubMed titles fenoldopam
Search PubMed titles/abstracts fenoldopam
Search UniChem for chemical match using the InChIKey TVURRHSHRRELCG-CYBMUJFWSA-N
Search UniChem for chemicals with the same backbone TVURRHSHRRELCG
Comments
This isomer is a component of the approved drug fenoldopam, which is used to treat severe hypertension. (-)-SKF-82526 is less active than (+)-SKF-82526. See our ligand entry for fenoldopam for more details.