TP-472

Ligand id: 9522

Name: TP-472

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 63.47
Molecular weight 333.15
XLogP 3.73
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-{6-acetylpyrrolo[1,2-a]pyrimidin-8-yl}-N-cyclopropyl-4-methylbenzamide
Database Links
PubChem CID 123773279
Search Google for chemical match using the InChIKey RPBMXJHQYJLPDN-UHFFFAOYSA-N
Search Google for chemicals with the same backbone RPBMXJHQYJLPDN
Search UniChem for chemical match using the InChIKey RPBMXJHQYJLPDN-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone RPBMXJHQYJLPDN
Comments
TP-472 is a potent BRD9/7 inhibitor tool compound that is cell permeable and active in vivo. TP-472 is one of the chemical tools in the Structural Genomics Consortium's Epigenetic Probes Library.