liver enriched antimicrobial peptide 2

Ligand id: 9734

Name: liver enriched antimicrobial peptide 2

Abbreviated name: LEAP2

Species: Human

Compound class Endogenous peptide in human, mouse or rat
LEAP2 is an endogenous peptide with antimicrobial properties, that is part of the humoral immune response to microbes. It is expressed in the liver. LEAP2 has also been identified as an endogenous antagonist of the appetite-stimulatory hormone, ghrelin, that is secreted in the stomach and which acts via the pituitary/hypothalamic ghrelin receptor (growth hormone secretagogue receptor, or GHSR) [1].
Gene symbol Gene name Species Precursor protein name Synonyms
LEAP2 liver enriched antimicrobial peptide 2 Human liver-expressed antimicrobial peptide 2 precursor LEAP-2, liver expressed antimicrobial peptide 2
Database Links
GtoPdb PubChem SID 354702210
UniProtKB Q969E1 (Hs)