naratuximab emtansine

Ligand id: 9949

Name: naratuximab emtansine

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
10238 naratuximab emtansine
Synonyms
IMGN-529 | IMGN529 | K7153A-SMCC-DM1
Comments
Naratuximab emtansine (IMGN529) is a CD37- targeting antibody drug conjugate carrying a potent anti-mitotic agent (maytansinoid DM1) payload. This ADC is being investigated for clinical efficacy as a treatment for B cell malignancies, with empahsis on diffuse large B cell lymphoma (DLBCL) in light of preliminary results from the phase 1 clinical trial NCT01534715 [4].
Database Links
Specialist databases
IMGT/mAb-DB 602
Other databases
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