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Synonyms: FZD8-Fc | OMP-54F28 | OMP54F28
Compound class:
Peptide or derivative
Comment: Ipafricept (OMP-54F28) is a fusion protein that fuses the FZD8 cysteine-rich domain to human IGHG1 Fc fragment [1]. It acts as a soluble decoy receptor for WNT ligands, and exhibits antitumour efficacy in vivo. Produced by OncoMed Pharmaceuticals.
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