isobutyric acid

Ligand id: 1060

Name: isobutyric acid

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 37.3
Molecular weight 88.05
XLogP 0.47
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
FFA3 receptor Hs Agonist Full agonist 4.3 – 4.8 pEC50 - 1,3
pEC50 4.3 – 4.8 [1,3]
FFA2 receptor Hs Agonist Full agonist 3.2 – 3.8 pEC50 - 2
pEC50 3.2 – 3.8 [2]