CGP 54626A

Ligand id: 1070

Name: CGP 54626A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 79.37
Molecular weight 407.12
XLogP 3.93
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
GABAB receptor Hs Antagonist Antagonist 8.1 – 8.2 pKi - 1,3
pKi 8.1 – 8.2 [1,3]
GABAB1 Rn Antagonist Antagonist 8.7 – 8.8 pIC50 - 2
pIC50 8.7 – 8.8 [2]