CGP 54626A

Ligand id: 1070

Name: CGP 54626A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 79.37
Molecular weight 407.12
XLogP 3.93
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
GABAB receptor Antagonist Antagonist 8.1 – 8.2 pKi - 1,3
pKi 8.1 – 8.2 [1,3]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
GABAB1 Antagonist Antagonist 8.7 – 8.8 pIC50 - 2
pIC50 8.7 – 8.8 [2]