Synonyms: compound 9f [PMID: 25782055] | RPX-7009 | RPX7009 | Vabomere (vaborbactam + meropenem)
vaborbactam is an approved drug (FDA (2017), EMA (2018))
Compound class:
Synthetic organic
Comment: Vaborbactam is a β-lactamase inhibitor [3]. Structurally it is based on a cyclic boronic acid pharmacophore.
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Bioactivity Comments |
Inhibits Escherichia coli recombinant SHV-12 β-lactamase with a Ki of 29 nM in vitro [3]. |