CGP 55845

Ligand id: 1088

Name: CGP 55845

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 79.37
Molecular weight 401.07
XLogP 4.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
GABAB receptor Hs Antagonist Antagonist 7.8 pKi - 2
pKi 7.8 [2]
GABAB receptor Rn Antagonist Antagonist 9.8 pIC50 - 1
pIC50 9.8 [1]