Synonyms: OBE101 [2] | SERC® | Vasomotal®
betahistine is an approved drug (FDA (1970s))
Compound class:
Synthetic organic
Comment: This is an orally delivered histamine receptor modulator that has weak agonist activity at histamine H1 receptors and more potent antagonist activity at the H3 receptor subtype [1].
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Bioactivity Comments |
Ki at rat H3 receptor is ~2 μM [1-2]. |