Synonyms: Pipram®
pipemidic acid is an approved drug
Compound class:
Synthetic organic
Comment: Pipemidic acid is from a series of derivatives of piromidic acid, with enhanced antibacterial activity against Gram-negative bacteria, including against Pseudomonas aeruginosa and some Gram-positive spp. [2]. It is a pyridopyrimidine, structurally related to and classed with the quinolone antibacterials.
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Bioactivity Comments |
The MIC for in vitro antibacterial activity is 1-3 μg/ml against Escherichia coli and 10-25 μg/ml against Pseudomonas aeruginosa [2-3]. |