Synonyms: BBC-0403
Compound class:
Synthetic organic
Comment: BBC0403 is reported as a inhibitor of bromodomain-containing (BRD) proteins, with some selectivity for BRD2 domains. It has been explored for efficacy as a treatment for osteoarthritis. BBC0403 inhibits NF-κB and MAPK signaling pathways.
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Bioactivity Comments |
BBC0403 prevents cartilage degradation in a mouse osteoarthritis model. |