Compound class:
Peptide or derivative
Comment: T20K (or [T20K]kB1) is a synthetic version of the plant-derived cyclotide cyclotide kalata B1. Compared to the natural cyclotide T20K has a Thr20Lys substitution. It is in preclinical development as an immunomodulator with potential application as a treatment for MS [1].
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Bioactivity Comments |
T20K has activity as an allosteric modulator at the κ-opioid receptor [2]. |