BW723C86

Ligand id: 161

Name: BW723C86

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 79.28
Molecular weight 286.11
XLogP 3.12
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
5-HT2B receptor Agonist Full agonist 7.3 – 8.6 pKi - 1-3
pKi 7.3 – 8.6 (Ki 5.01x10-8 – 2.51x10-9 M) [1-3]
5-HT2A receptor Agonist Full agonist 7.2 pKi - 2
pKi 7.2 [2]
5-HT2C receptor Agonist Full agonist 6.9 – 7.1 pKi - 2-3
pKi 6.9 – 7.1 [2-3]