AH6809

Ligand id: 1896

Name: AH6809

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 72.83
Molecular weight 298.08
XLogP 3.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
EP2 receptor Mm Antagonist Antagonist 6.5 pKi - 3
pKi 6.5 [3]
EP2 receptor Rn Antagonist Antagonist 6.3 pKi - 2
pKi 6.3 [2]
EP1 receptor Hs Antagonist Antagonist 5.9 – 6.0 pKi - 1,4
pKi 5.9 – 6.0 [1,4]
EP1 receptor Rn Antagonist Antagonist 5.9 pKi - 2
pKi 5.9 [2]
EP2 receptor Hs Antagonist Antagonist 5.9 pKi - 1
pKi 5.9 [1]
DP1 receptor Hs Antagonist Antagonist 5.8 pKi - 1
pKi 5.8 [1]
EP3 receptor Hs Antagonist Antagonist 5.8 pKi - 1
pKi 5.8 (Ki 1.6x10-6 M) EP3-III isoform [1]