AH6809

Ligand id: 1896

Name: AH6809

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 72.83
Molecular weight 298.08
XLogP 3.18
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
EP1 receptor Antagonist Antagonist 5.9 – 6.0 pKi - 1,4
pKi 5.9 – 6.0 [1,4]
EP2 receptor Antagonist Antagonist 5.9 pKi - 1
pKi 5.9 [1]
DP1 receptor Antagonist Antagonist 5.8 pKi - 1
pKi 5.8 [1]
EP3 receptor Antagonist Antagonist 5.8 pKi - 1
pKi 5.8 (Ki 1.6x10-6 M) EP3-III isoform [1]
Selectivity at mouse GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
EP2 receptor Antagonist Antagonist 6.5 pKi - 3
pKi 6.5 [3]
Selectivity at rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
EP2 receptor Antagonist Antagonist 6.3 pKi - 2
pKi 6.3 [2]
EP1 receptor Antagonist Antagonist 5.9 pKi - 2
pKi 5.9 [2]