compound rac-16 [PMID: 15603962]

Ligand id: 2333

Name: compound rac-16 [PMID: 15603962]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 52.6
Molecular weight 386.05
XLogP 3.48
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at ion channels
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
KCa3.1 Hs Channel blocker Inhibition 7.9 – 8.0 pIC50 - 1-2
pIC50 7.9 – 8.0 [1-2]