Ligand id: 3058

Name: CP-294838

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 66.84
Molecular weight 435.1
XLogP 4.98
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at rat enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
squalene synthase Inhibitor Inhibition 6.9 pIC50 - 1
pIC50 6.9 (1.3x10-7 M) [1]
Description: in vitro, soluable microsomal enzymes purified from rat and human liver microsomes
Conditions: Concentration of FPP: 20µM