compound 15 [Biller et al., 1993]

Ligand id: 3131

Name: compound 15 [Biller et al., 1993]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 10
Topological polar surface area 123.68
Molecular weight 402.14
XLogP 3.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at rat enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
squalene synthase Inhibitor Inhibition 6.9 pIC50 - 1
pIC50 6.9 (IC50 1.25x10-7 M) [1]
Description: Tested for inhibitory potency against rat liver microsomal squalene synthase