Ligand Id: 3337
Ligand name MRS2690

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 18
Hydrogen bond donors 7
Rotatable bonds 11
Topological polar surface area 304.18
Molecular weight 626
XLogP -3.96
No. Lipinski's rules broken 3

Molecular properties generated using the CDK

Summary Biological activity References Structure Similar ligands

Selectivity data from the Guide to Receptors and Channels (GRAC), 5th Edition.

Selectivity at human targets (unless otherwise stated)
Key to terms and symbols Click column headers to sort
Receptor Type Action Affinity Units Concentration range (M) Reference
P2Y14 receptor Agonist Agonist 6.64 pEC50 - 1-2

Selectivity data from IUPHAR-DB

Selectivity at human GPCRs
Key to terms and symbols Click column headers to sort
Receptor Type Action Affinity Units Concentration range (M) Reference
P2Y14 receptor Agonist Agonist 6.64 pEC50 - 1-2

Please note: The activity data given on this ligand page represents selected literature values and may not include all reported data.
For more details please contact: curators@iuphar-db.org