Ligand id: 3421

Name: (S)-(+)-CBPG

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 3
Topological polar surface area 100.62
Molecular weight 185.07
XLogP -3.2
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at Rat GPCRs
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
mGlu5 receptor Agonist Partial agonist 4.3 pEC50 - 1
pEC50 4.3 (EC50 4.7x10-5 M) [1]
mGlu1 receptor Antagonist Antagonist 4.2 pIC50 - 1
pIC50 4.2 (IC50 6.7x10-5 M) [1]
Ligand mentioned in the following text fields