[3H]ETB-TBOA

Ligand id: 4492

Name: [3H]ETB-TBOA    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 4
Rotatable bonds 10
Topological polar surface area 138.95
Molecular weight 386.15
XLogP 1.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at rat transporters
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Excitatory amino acid transporter 4 None Binding 7.9 pKd - 1
pKd 7.9 (Kd 1.14x10-8 M) [1]
Excitatory amino acid transporter 1 None Binding 7.8 pKd - 1
pKd 7.8 (Kd 1.55x10-8 M) [1]
Excitatory amino acid transporter 2 None Binding 7.8 pKd - 1
pKd 7.8 (Kd 1.62x10-8 M) [1]
Excitatory amino acid transporter 5 None Binding 7.6 pKd - 1
pKd 7.6 (Kd 2.48x10-8 M) [1]
Excitatory amino acid transporter 3 None Binding 6.5 pKd - 1
pKd 6.5 (Kd 3.2x10-7 M) [1]
Ligand mentioned in the following text fields