gemcitabine

Ligand id: 4793

Name: gemcitabine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 108.05
Molecular weight 264.08
XLogP -0.77
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
Equilibrative nucleoside transporter 2
Solute carrier family 28 member 3
Sodium/nucleoside cotransporter 1 1
Equilibrative nucleoside transporter 1
Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
ribonucleotide reductase catalytic subunit M1 Hs Inhibitor Inhibition - - - 2
[2]
ribonucleotide reductase regulatory subunit M2 Hs Inhibitor Inhibition - - - 2
[2]