gemcitabine

Ligand id: 4793

Name: gemcitabine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 4
Rotatable bonds 2
Topological polar surface area 108.05
Molecular weight 264.08
XLogP -0.77
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Transporters Moving this Compound Across a Lipid Membrane
Transporter EC number Reaction Reference
Equilibrative nucleoside transporter 2
Solute carrier family 28 member 3
Sodium/nucleoside cotransporter 1 1
Equilibrative nucleoside transporter 1
Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
ribonucleotide reductase catalytic subunit M1 Inhibitor Inhibition - - - 2
[2]
ribonucleotide reductase regulatory subunit M2 Inhibitor Inhibition - - - 2
[2]